Finding
Paper
Citations: 0
Abstract
Objective To evaluate the effects of oxygen free radical on causes of primary acute angle closure glaucoma(PACG).Methods 5ml vein blood of 38 patients with PACG were extracted.Levels of malondialdehyde (MDA) and the activity of superoxide dismutas (SOD) were determined with MDA regeant box and SOD regeant box.38 normal persons were selected as control group.Results The levels of lipid peroxidation (LPO) and the activity of superoxide dismutase in PACG group were significantly different from those in the normal control group. Conclusion The factors of oxygen free radical (·O - 2) participate in the processes of the di sease coming on and become a potential pathogenesis of PACG.·O - 2 destroies red cell membranes by the function of LPO,decreases the mobility of red cell membranes and increase blood viscosity.These factors result in obstruction of miccirculation,hyperemia of ciliary,ischemia,edema and accelerate chamber angle closed.
Authors
Y. Hui
Journal
Journal of Harbin Medical University