Background: Obesity and its related disorders are the cause of cardiovascular disease and an increased risk of morbidity and mortality. Nevertheless, the results of studies indicated that exercise training have beneficial health effects on obesity and risk markers of cardiovascular disease. Therefore, the purpose of this study was to examine the effect of 8 weeks of resistance training on lipocalin2 (LCN2) and fatty acid binding protein (FABP) in obese adult males. Materials and Methods: In this quasi-experimental study, the obese adult men (n=24) were randomly assigned into Control and Exercise groups. Exercise group was participated in a resistance exercise program with 50-80 of one Repeated- Maximum (IRM) intensity for 8 weeks (three times per week). Venous blood samples were collected before and after the exercise. Moreover, body composition indexes were measured at pre- and post-training programme Results: Resistance exercise caused a significant decrease in the body fat percent, waist circumference and waist to hip ratio (WHR) in Exercise group (P<0.05). Moreover, the results indicated a significant decrease in Exercise group for LCN2 concentration after resistance training (P=0.002) compared to Control group (P=0.799). Also a significant decrease in FABP4 concentration was found in Exercise group (P=0.002). Conclusion: The results of the present study suggest that 8 weeks of resistance exercise improve body composition and decrease the new cardiovascular biomarkers in obese men. However, further research is necessary to understand the molecular mechanisms involved.
S. Atashak, Adel Ahmadi-Zad