Finding
Laboratory should establish its own referent ranges for bilirubin determination or perform a correlation study if two different methods for bilirubin measurement exit.
Paper
Comparison of the Results between Conventional Heavy Method and Multilayer Film Method of Serum Bilirubin Determination
Observational Study
Citations: 0
Full textAbstract
Objective To compare and analyse the difference between the two methods(conventional heavy nitrogen method and multilayer film method)of serum bilirubin.Method 40 hyperbilirubinemia serum sample was selected randomly,the bilirubin of the samples was measured with biochemistry analysor of HITACH 7600 and VITROR 250,and SPSS 10.0 was used to analyse the data.Results There was no significant difference between the two methods for total bilirubin determination(P0.05),yet the difference between the unconjugated bilirubin and conjugated bilirubin was highly significant(P0.001).Conclusion For hyperbilirubinemi sample,the two methods may produce different results because of the presence of δ-bilirubin.Laboratory should establish its own referent ranges for bilirubin determination or perform a correlation study if two different methods for bilirubin measurement exit.Unconjugated bilirubin result obtained by multilayer film method may be more sensitive for diagnosis.
Authors
Gu Bin-quan
Journal
Chinese Journal of Hemorheology