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Sesame seeds are known for their numerous health benefits, which have been supported by various studies. Below is an overview of the key health benefits of sesame seeds, organized into relevant sections.
Lipid Profile Improvement
Sesame seeds have been shown to positively affect lipid profiles. Studies indicate that sesame seed consumption can significantly decrease total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and the ratio of LDL-C to high-density lipoprotein cholesterol (HDL-C)2 3 6. These changes contribute to a reduced risk of cardiovascular diseases.
Antioxidant Properties
Sesame seeds are rich in antioxidants, which help combat oxidative stress. Research has demonstrated that sesame seed supplementation increases the activities of antioxidant enzymes such as glutathione peroxidase (GPX) and superoxide dismutase (SOD), while reducing lipid peroxidation markers like thiobarbituric acid reactive substances (TBARS)3 6. Additionally, serum gamma-tocopherol (GT) levels have been shown to increase with sesame seed consumption, further enhancing antioxidant status1 2.
Anti-inflammatory Effects
Sesame seeds exhibit anti-inflammatory properties. Studies on both humans and animals have shown that sesame seed consumption can reduce markers of inflammation, such as high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6)4 8. These effects are beneficial in managing conditions like osteoarthritis and atherosclerosis.
Blood Glucose Control
Sesame seeds and sesame oil have been found to improve blood glucose control. In diabetic patients, sesame seed supplementation has been shown to significantly reduce fasting blood glucose and glycated hemoglobin (HbA1c) levels5 7 9. This makes sesame seeds a valuable dietary addition for managing diabetes.
Hormonal Balance
Sesame seeds may also influence hormonal balance, particularly in postmenopausal women. Studies have shown that sesame ingestion can increase serum sex hormone-binding globulin and urinary 2-hydroxyestrone, suggesting potential benefits in hormone regulation2.
Liver and Kidney Function
Sesame seeds have been found to improve liver and kidney function. In studies involving diabetic rats, sesame seed oil supplementation significantly improved biomarkers of hepatic and renal health5. This indicates potential protective effects against diabetes-related organ damage.
Conclusion
Sesame seeds offer a range of health benefits, including improvements in lipid profiles, antioxidant status, anti-inflammatory effects, blood glucose control, hormonal balance, and liver and kidney function. These benefits make sesame seeds a valuable addition to a healthy diet, particularly for individuals managing conditions like hyperlipidemia, diabetes, and inflammation-related diseases.
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