What Is Bacillus Coagulans? Other Names: B. Coagulans, Bacillus Probiotics, Lactobacillus Sporogenes

What is Bacillus Coagulans?

This post was written with Consensus AI Academic Search Engine – please read our Disclaimer at the end of this article. Bacillus coagulans is a spore-forming, lactic acid-producing bacterium that has gained attention for its probiotic properties. It is widely used in food and feed additives due to its ability to survive harsh conditions, such as those found in the gastrointestinal tract, and its potential health benefits. Other names include: B. Coagulans, Bacillus Bacteria, Bacillus Probiotics, Bactéries Bacilles, Bactéries à Gram Positif Sporogènes, Bactérie Gram Positive en Forme de Bâtonnet, Gram Positive Spore-Forming Rod, L. Sporogenes, Lactobacillus Sporogenes, Lactobacillus Sporogènes, Probiotic, Probiotique, Spore-Forming Lactobacillus, Weizmannia coagulans.

Effects on Intestinal Health

In humans, Bacillus coagulans SNZ 1969 has been shown to improve intestinal motility and reduce constipation symptoms by altering the gut microbiota composition2. Similarly, Bacillus coagulans GBI-30, 6086 has been found to decrease symptoms of upper respiratory and gastrointestinal tract infections in children by modulating immune-related proteins3.

Applications in Animal Health

Bacillus coagulans is also used in animal feed to enhance growth performance, antioxidant capacity, and immune function. In broilers, it has been shown to improve body weight and gut health by increasing antioxidant enzyme levels and modulating the gut microbiota4. In piglets, Bacillus coagulans supplementation has been found to reduce intestinal injury caused by pathogens and improve gut microbiota balance5.

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Probiotic Mechanisms and Health Benefits of Bacillus Coagulans

Bacillus coagulans has been shown to improve intestinal health by inhibiting the growth of harmful bacteria and promoting the growth of beneficial bacteria. It enhances the intestinal microecological environment, promotes intestinal development, and boosts intestinal function1. In particular, Bacillus coagulans TL3 has been found to regulate signaling pathways in the cecal tissue of rats, protecting the intestine from inflammation and oxidative damage1.

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Uses of Bacillus Coagulans

Gut Health and Constipation Relief: Bacillus coagulans has been shown to improve intestinal motility and alleviate symptoms of constipation by altering gut microbiota composition, making it beneficial for individuals with mild intermittent constipation1.

Immune Function and Infection Reduction: It can modulate immune-related proteins, reducing symptoms of upper respiratory and gastrointestinal tract infections in children, and enhancing immune responses in broilers4 2.

Growth and Health in Animals: In broilers and common carp, Bacillus coagulans improves growth performance, antioxidant capacity, and gut health, serving as an effective alternative to antibiotics2 3.

Digestive Health in the Elderly: When combined with digestive enzymes, Bacillus coagulans can significantly improve symptoms of indigestion in the geriatric population6.

Irritable Bowel Syndrome (IBS) Management: It has been effective in reducing IBS symptoms in children and adults, improving pain intensity, stool consistency, and overall bowel habit satisfaction7 10.

Rheumatoid Arthritis Symptom Relief: Bacillus coagulans may help alleviate symptoms of rheumatoid arthritis, improving pain and functional capacity when used alongside standard medications9.

Depression and IBS: It has shown efficacy in managing major depressive disorder in patients with IBS, improving both depression and IBS symptoms10.

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Adverse Effects of Bacillus Coagulans

Observed Effects and Benefits

Intestinal Health and Microbiota Regulation: Bacillus coagulans has been shown to improve intestinal health by reducing harmful bacteria and promoting beneficial bacteria in the gut. It helps in maintaining the balance of gut microbiota, which can be beneficial in conditions like infections and dysbiosis1 2 3 4 5 6.

Immune Modulation: The probiotic has been observed to modulate immune responses, reducing inflammation and enhancing immune function. It decreases pro-inflammatory cytokines and increases anti-inflammatory factors, which can be beneficial in managing infections and inflammatory conditions3 4 6 7 8.

Growth Performance in Animals: In studies involving animals like piglets and broilers, Bacillus coagulans supplementation improved growth performance, reduced intestinal injury, and enhanced overall health, suggesting its potential as a growth promoter in livestock2 3 4 6.

Safety and Tolerance: Across various studies, Bacillus coagulans has been well-tolerated without significant adverse events reported. It is considered safe for consumption in both humans and animals, with no negative impact on nutrient digestibility or general health5 9 10.

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How has Bacillus Coagulans Improved Patient Outcomes?

Improvements in Specific Conditions

Non-Alcoholic Fatty Liver Disease (NAFLD): Supplementation with Bacillus coagulans plus inulin significantly reduced liver inflammation markers and hepatic steatosis in NAFLD patients, indicating its beneficial role in managing liver health1.

Constipation and Gut Motility: In healthy adults with mild intermittent constipation, Bacillus coagulans improved colonic transit time, bowel movement frequency, and reduced bowel discomfort, likely through alterations in gut microbiota composition2.

Irritable Bowel Syndrome (IBS): Bacillus coagulans has been effective in reducing IBS symptom severity, improving stool consistency, and enhancing overall bowel satisfaction. It also showed a positive impact on mental well-being in IBS patients with comorbid depression3 6 7 9 10.

Rheumatoid Arthritis (RA): Patients with RA experienced improvements in pain and functional capacity when Bacillus coagulans was used as an adjunct therapy, suggesting its anti-inflammatory benefits5.

Post-Surgical Recovery: In gynecological laparoscopy patients, Bacillus coagulans helped in faster recovery of intestinal function by modulating gut microbiota and metabolic pathways8.

Obesity and Metabolic Health: In obese patients undergoing sleeve gastrectomy, Bacillus coagulans contributed to improved metabolic outcomes, such as reduced triglycerides and LDL cholesterol levels4.

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Common Complaints Associated with Bacillus Coagulans Use

Gastrointestinal Symptoms: While Bacillus coagulans is generally used to improve gastrointestinal health, some individuals might experience mild gastrointestinal symptoms such as flatulence. However, in one study, the incidence of flatulence was actually reduced with Bacillus coagulans supplementation1.

No Significant Adverse Effects Noted: The studies reviewed did not report significant adverse effects associated with Bacillus coagulans. Instead, they focused on its benefits, such as reducing symptoms of upper respiratory tract infections and gastrointestinal tract infections in children1, protecting against intestinal inflammation and oxidative damage in rats2, and improving intestinal motility and constipation perception in adults3.

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Disclaimer

The content presented in this blog is generated by Consensus, an AI-powered academic search engine, and is based on publicly available scientific literature. While every effort is made to provide accurate, up-to-date, and well-researched information, the content is intended for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before making any decisions regarding medical conditions, treatments, or medications. The AI system’s analysis may not cover all perspectives, emerging research, or individual cases, and it is not a substitute for professional expertise. Neither the blog publisher nor the developers of the AI-powered search engine are responsible for any actions taken based on the information provided in this content. Use of this information is at your own risk. Citations to the original scientific studies are included for reference, but these studies should be reviewed in full and interpreted with the guidance of a healthcare or research professional.

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