1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.

doi:10.1016/j.ejmech.2018.09.067

Paper

1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.

Published Nov 1, 2018 · Alice Ameryckx, Léopold Thabault, L. Pochet

European journal of medicinal chemistry

Q2 SJR score

23

Citations

2

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

The 1-(2-hydroxybenzoyl)-thiosemicarbazide motif shows promise for developing novel antibacterial compounds with low cytotoxicity and a bactericidal mechanism against multidrug-resistant bacteria.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.

References

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