1-Phenyl-3,3-di(1H-pyrazol-1-yl)propan-1-one

doi:10.3390/m1472

Paper

1-Phenyl-3,3-di(1H-pyrazol-1-yl)propan-1-one

Published Oct 26, 2022 · M. Gotsko, I. Saliy, A. Vashchenko

Molbank

Q4 SJR score

2

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0

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Abstract

The title compound, 1-phenyl-3,3-di(1H-pyrazol-1-yl)propan-1-one, was synthesized in a 52% yield for the first time by a one-step reaction between 1H-pyrazole and 1-phenylprop-2-yn-1-one (their ratio being 2:1) in solid Al2O3 at room temperature. The product was characterized by 1H-NMR, 13C-NMR, IR spectroscopy, X-Ray diffraction and elemental analysis.

Study Snapshot

This study demonstrates a novel method for synthesizing 1-phenyl-3,3-di(1H-pyrazol-1-yl)propan-1-one in a 52% yield by combining 1H-pyrazole and 1-phenylprop-2-yn-1-one in solid

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

1-Phenyl-3,3-di(1H-pyrazol-1-yl)propan-1-one

References

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Citations

New Copper Complexes with N,O-Donor Ligands Based on Pyrazole Moieties Supported by 3-Substituted Acetylacetone Scaffolds

New copper complexes with N,O-donor ligands based on pyrazole moieties were synthesized using 3-substituted acetylacetone scaffolds, providing efficient access to synthetically useful ketone compounds.

Addition of pyrazoles to α,β-acetylenic aryl(hetaryl) ketones in solid Al_2O_3: synthesis of 3-pyrazolylenones and 3,3-dipyrazolylpropanones

Pyrazoles can be added to,-acetylenic aryl(hetaryl) ketones in solid Al2O3 for the one-pot synthesis of 3-pyrazolylenones and 3,3-dipyrazolylpropanones, promising drug precursors