Paper

2-Methoxyestradiol causes functional repression of transforming growth factor β3 signaling by ameliorating Smad and non-Smad signaling pathways in immortalized uterine fibroid cells.

Published Jul 1, 2012 · S. Salama, Concepcion R. Diaz-Arrastia, G. Kilic

Fertility and sterility

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Abstract

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In Vitro Study

Study Snapshot

2-methoxyestradiol inhibits TGF-3-induced profibrotic effects in uterine fibroid cells by improving both Smad-dependent and Smad-independent signaling pathways.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

2-Methoxyestradiol causes functional repression of transforming growth factor β3 signaling by ameliorating Smad and non-Smad signaling pathways in immortalized uterine fibroid cells.

References

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