2-Methoxyestradiol causes functional repression of transforming growth factor β3 signaling by ameliorating Smad and non-Smad signaling pathways in immortalized uterine fibroid cells.

doi:10.1016/j.fertnstert.2012.04.002

Paper

DOI: 10.1016/j.fertnstert.2012.04.002

2-Methoxyestradiol causes functional repression of transforming growth factor β3 signaling by ameliorating Smad and non-Smad signaling pathways in immortalized uterine fibroid cells.

Published Jul 1, 2012 · S. Salama, Concepcion R. Diaz-Arrastia, G. Kilic

Fertility and sterility

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Study Snapshot

2-methoxyestradiol inhibits TGF-3-induced profibrotic effects in uterine fibroid cells by improving both Smad-dependent and Smad-independent signaling pathways.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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