Síntese do 4-((5-acetamido-2-hidroxifenil) diazenil) benzenossulfônico, um Azobenzeno Derivado do Acetaminofeno, e Avaliaçao do seu Potencial como Indicador de Valor de pH

doi:10.21577/1984-6835.20160103

Paper

Síntese do 4-((5-acetamido-2-hidroxifenil) diazenil) benzenossulfônico, um Azobenzeno Derivado do Acetaminofeno, e Avaliaçao do seu Potencial como Indicador de Valor de pH

Published Aug 24, 2016 · Délis G. Guimarães, A. Gonsalves, C. Araújo

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Abstract

Strong absorption and bright colours of the azobenzene have attracted attention for the development of chemical sensors of this class of compounds, such as acid-base indicators. The present work describes the synthesis of a derivative of the drug acetaminophen, the azobenzene 4 - ((5-acetamido-2-hydroxyphenyl) diazenil) benzenesulfonic, and evaluation of the potential of this as a pH value indicator. The azobenzene was obtained in 77% yield and low cost, and shown to be a promising pH value indicator with good solubility in water, readily distinguishable color change in the zone turning, wide range of usable concentration and pK a values calculated: 9,072; 9,322 e 9,265. Thus it can be used as pH value indicator of basic band, and the results may contribute to the development of new synthetic compounds with acid-base indicator activity with low production cost.

Study Snapshot

The azobenzene derivative from acetaminophen, 4-((5-acetamido-2-hydroxyphenyl) diazenil) benzenosulfonic, shows promising potential as a pH value indicator with good solubility in water, readily distinguishable color change, and

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Síntese do 4-((5-acetamido-2-hidroxifenil) diazenil) benzenossulfônico, um Azobenzeno Derivado do Acetaminofeno, e Avaliaçao do seu Potencial como Indicador de Valor de pH

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