4-Substituted 4-(1H-1,2,3-triazol-1-yl)piperidine: novel C7 moieties of fluoroquinolones as antibacterial agents.

doi:10.1016/j.bmcl.2010.03.044

Paper

4-Substituted 4-(1H-1,2,3-triazol-1-yl)piperidine: novel C7 moieties of fluoroquinolones as antibacterial agents.

Published May 1, 2010 · Xiaoguang Huang, Ai-Hua Zhang, Dongliang Chen

Bioorganic & medicinal chemistry letters

Q2 SJR score

45

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Abstract

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In Vitro Study

Study Snapshot

New fluoroquinolones show comparable antibacterial activity against both susceptible and multidrug-resistant strains, particularly Staphylococcus aureus and Staphylococcus epidermidis, compared to ciprofloxacin and vancomycin.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

4-Substituted 4-(1H-1,2,3-triazol-1-yl)piperidine: novel C7 moieties of fluoroquinolones as antibacterial agents.

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