6α-[18F]Fluoroprogesterone: Synthesis via halofluorination-oxidation, receptor binding and tissue distribution

doi:10.1016/0969-8051(94)00142-7

Paper

DOI: 10.1016/0969-8051(94)00142-7

6α-[18F]Fluoroprogesterone: Synthesis via halofluorination-oxidation, receptor binding and tissue distribution

Published Jul 1, 1995 · Y. Choe, T. Bonasera, D. Chi

Nuclear Medicine and Biology

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Study Snapshot

6-[18F]fluoroprogesterone shows potential as an imaging agent for progesterone receptor-positive breast cancer, with low uterine uptake and high fat uptake.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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References

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11 beta-F-DHT shows promising in vivo prostate cancer imaging properties, while 11 beta-F-19-nor-DHT shows low prostate uptake and rapid metabolism, affecting its biodistribution properties.

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Fluorine-18-labeled progestin 16 alpha, 17 alpha-dioxolanes: development of high-affinity ligands for the progesterone receptor with high in vivo target site selectivity.

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16 beta-([18F]fluoro)estrogens: systematic investigation of a new series of fluorine-18-labeled estrogens as potential imaging agents for estrogen-receptor-positive breast tumors.

New fluorine-18-labeled estrogens show potential as estrogen receptor-positive breast tumor imaging agents with improved uptake characteristics and binding selectivity indices.

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DOI: 10.1016/j.jsbmb.2013.04.003

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DOI: 10.1016/j.tvjl.2009.06.007

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