Paper
Triethylsilane–Trifluoroacetic Acid
Published Apr 15, 2001 · J. L. Fry
2
Citations
0
Influential Citations
Abstract
[617-86-7] C6H16Si (MW 116.31) InChI = 1S/C6H16Si/c1-4-7(5-2)6-3/h7H,4-6H2,1-3H3 InChIKey = AQRLNPVMDITEJU-UHFFFAOYSA-N [599-00-8] C2HF3O2 (MW 114.03) InChI = 1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7) InChIKey = DTQVDTLACAAQTR-UHFFFAOYSA-N (useful reducing agent combination for ‘ionic hydrogenation’ of many functional groups1) Physical Data: see Triethylsilane and Trifluoroacetic Acid. Solubility: Et3SiH: insol H2O; sol hydrocarbons, chlorocarbons, ethers. CF3CO2H: sol H2O, chlorocarbons, ethers. Form Supplied in: both are colorless liquids; widely available in pure form. Purification: simple distillation, if needed. Handling, Storage, and Precautions: triethylsilane is a flammable, nonpyrophoric liquid, physically similar to comparable hydrocarbons. Proper precautions should be taken to vent possible hydrogen buildup when opening vessels in which triethylsilane is stored. As with all organosilicon hydrides, it is capable of releasing hydrogen gas upon storage, particularly in the presence of acids, bases, or fluoride-releasing salts. Trifluoroacetic acid is a corrosive, toxic acid that produces serious chemical burns upon contact with skin.
Triethylsilane and trifluoroacetic acid are useful reducing agents for ionic hydrogenation of many functional groups, but proper handling and storage are crucial to avoid potential hazards.
Full text analysis coming soon...