OBJECTIVE To analyze the cause of Acinetobacter baumannii resistance to β-lactam and the aminoglycoside-modifying antibacterials. METHODS Three-dimensional test was used to analyze and classify the β-lactamases. Proper primers was used to do PCR and determined by sequencing. RESULTS A. baumannii clinical isolate harbored blaOXA2-23,blaTEM and blaADC genes and aac(3)-Ⅰ,aac(6')-Ⅰb and ant(3″)-Ⅰ aminoglycoside-modifying enzyme genes. CONCLUSIONS An A. baumannii strain which carries TEM,OXA-23,ADC β-lactams and aac(3)-Ⅰ,aac(6')-Ⅰb,ant(3″)-Ⅰ aminoglycoside-modifying enzyme genes is detected.

Acinetobacter baumannii strains with TEM,OXA-23,ADC -lactamases and aac(3)-I,aac(6')-Ib,ant(3′′)-I aminoglycoside-modifying enzyme genes are resistant to -

A Clinical Acinetobacter baumannii Strain Carrying Beta-lactamases and Aminoglycoside-modifying Enzyme Genes

Key Takeaway: Acinetobacter baumannii strains with TEM,OXA-23,ADC -lactamases and aac(3)-I,aac(6')-Ib,ant(3′′)-I aminoglycoside-modifying enzyme genes are resistant to -