Paper
Anti-apoptotic activity of hydroxytyrosol and hydroxytyrosyl laurate.
Published May 1, 2013 · S. Burattini, S. Salucci, V. Baldassarri
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Q1 SJR score
60
Citations
1
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Hydroxytyrosol and its ester hydroxytyrosyl laurate show greater anti-apoptotic activity than HyT, suggesting potential for novel therapeutic strategies.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
Full text analysis coming soon...
References
Investigation into the biological properties of the olive polyphenol, hydroxytyrosol: mechanistic insights by genome-wide mRNA-Seq analysis
Hydroxytyrosol, a polyphenol found in olive oil, has antioxidant, anti-atherogenic, and anti-cancer properties, with potential mechanisms of action including upregulation of antioxidant proteins and chemoprevention of cancer.
2012·45citations·Haloom Rafehi et al.·Genes & Nutrition
Genes & Nutrition
Mecanismos de perda muscular da sarcopenia
Sarcopenia in rheumatoid arthritis patients is caused by various intracellular signaling pathways, leading to reduced muscle strength and functional impairment.
2012·36citations·V. N. Teixeira et al.·Revista Brasileira De Reumatologia
Revista Brasileira De Reumatologia
Olive oil hydroxytyrosol reduces toxicity evoked by acrylamide in human Caco-2 cells by preventing oxidative stress.
Olive oil hydroxytyrosol reduces acrylamide toxicity in human Caco-2 cells by preventing oxidative stress and partially restraining the apoptotic pathway activated by acrylamide.
2011·64citations·I. Rodriguez-Ramiro et al.·Toxicology
Toxicology
An efficient, economical synthesis of hydroxytyrosol and its protected forms via Baeyer–Villiger oxidation
This study developed an efficient, economical method for synthesising hydroxytyrosol and its orthogonally-protected forms from inexpensive tyrosol using Baeyer-Villiger oxidation.
2011·19citations·G. Piersanti et al.·Tetrahedron Letters
Tetrahedron Letters
Mitochondrial dynamic remodeling in strenuous exercise-induced muscle and mitochondrial dysfunction: regulatory effects of hydroxytyrosol.
Hydroxytyrosol supplementation can improve endurance capacity and prevent exercise-induced renal and immune system damage by regulating mitochondrial dynamic remodeling and enhancing antioxidant defenses.
2011·106citations·Zhihui Feng et al.·Free radical biology & medicine
Free radical biology & medicine
Alkyl hydroxytyrosyl ethers show protective effects against oxidative stress in HepG2 cells.
Alkyl hydroxytyrosyl ethers show protective effects against oxidative stress in HepG2 cells, similar to or higher than those of their precursor, hydroxytyrosol, due to their lipophilic nature.
2011·37citations·G. Pereira-Caro et al.·Journal of agricultural and food chemistry
Journal of agricultural and food chemistry
Oleuropein and derivatives from olives as Tau aggregation inhibitors
Oleuropein and its derivatives from olives can prevent tau protein aggregation, potentially benefiting Alzheimer's disease and tauopathies.
2011·159citations·Anthony Daccache et al.·Neurochemistry International
Neurochemistry International
Olive oil reduces oxidative damage in a 3-nitropropionic acid-induced Huntington's disease-like rat model
Extra-virgin olive oil and hydroxytyrosol effectively protect the brain against oxidative stress caused by 3-nitropropionic acid, potentially reducing the risk of neurodegenerative diseases.
2011·72citations·I. Tasset et al.·Nutritional Neuroscience
Nutritional Neuroscience
Autophagy up-regulation by early weaning in the liver, spleen and skeletal muscle of piglets
Early weaning in piglets induces autophagy in liver, spleen, and skeletal muscle, potentially aiding in maintaining cellular homeostasis and energy balance.
2011·15citations·Shaojin Zhang et al.·British Journal of Nutrition
British Journal of Nutrition
Citations
Hydroxytyrosol: A Promising Therapeutic Agent for Mitigating Inflammation and Apoptosis
Hydroxytyrosol shows potential as a therapeutic agent for mitigating inflammation and apoptosis, potentially improving patient outcomes in chronic diseases like cardiovascular problems and neurological conditions.
2024·2citations·Wafa Ali Batarfi et al.·Pharmaceutics
Pharmaceutics
Hydroxytyrosol promotes random skin flap survival by activating SIRT1-mediated enhancement of autophagy
Hydroxytyrosol promotes random skin flap survival by activating SIRT1-mediated autophagy, reducing necrotic areas and edema in surgical tissue reconstruction.
2024·0citations·Siyuan Chen et al.·Journal of Functional Foods
Journal of Functional Foods
The Bioactivity of a Hydroxytyrosol-Enriched Extract Originated after Direct Hydrolysis of Olive Leaves from Greek Cultivars
Direct hydrolysis of olive leaves produces hydroxytyrosol-enriched extracts with significant in vitro antioxidant and DNA-protective properties, potentially benefiting pharmaceutical, food, and cosmetic industries.
2024·5citations·Maria Kourti et al.·Molecules
Molecules
Multi-Organ Morphological Findings in a Humanized Murine Model of Sickle Cell Trait
Sickle cell trait (SCT) carriers show endothelial alterations in multiple organs, with the lung showing the most significant changes, while the heart shows the least affected tissue.
2023·2citations·M. Trucas et al.·International Journal of Molecular Sciences
International Journal of Molecular Sciences
Role of Hydroxytyrosol and Oleuropein in the Prevention of Aging and Related Disorders: Focus on Neurodegeneration, Skeletal Muscle Dysfunction and Gut Microbiota
Hydroxytyrosol and oleuropein, found in extra virgin olive oil, may help prevent age-related neurodegeneration, skeletal muscle dysfunction, and gut microbiota imbalances.
2023·28citations·L. Micheli et al.·Nutrients
Nutrients
Dietary supplements in lymphedema
GARLIVE®, a dietary supplement containing hydroxytyrosol from olives, shows potential as a natural candidate for lymphedema treatment by reducing inflammation and leukotriene B4 synthesis.
2022·0citations·G. Bonetti et al.·Journal of Preventive Medicine and Hygiene
Journal of Preventive Medicine and Hygiene
Effect of a dietary supplement on the reduction of lymphedema-progression in mouse tail-cut model.
Garlive®, a dietary supplement containing hydroxytyrosol, spermidine, hesperidin, and vitamin A, effectively prevents lymphedema progression and promotes wound healing in a mouse tail-cut model.
2021·4citations·Bhusan Tripathi et al.·European review for medical and pharmacological sciences
European review for medical and pharmacological sciences
Hydroxytyrosol-Fortified Foods Obtained by Supercritical Fluid Extraction of Olive Oil
This study developed a new process for obtaining hydroxytyrosol-enriched foods by supercritical fluid extraction of olive oil, resulting in quantitative transfer and maintaining nutraceutical characteristics after cooking.
2021·7citations·L. Bartella et al.·Antioxidants
Antioxidants