Abstract Important advances in the understanding and management of venous thromboembolism (VTE) have enhanced our ability to diagnose, prevent, and treat VTE. In this narrative review, we discuss how recent advances in the understanding and management of VTE are changing practice, highlight ongoing unmet needs in VTE management, and outline how novel therapeutic targets with little or no influence on hemostasis may help address these unmet needs.

Recent advances in venous thromboembolism management are changing practice, and novel therapeutic targets with minimal hemostasis influence may help address unmet needs.

Advances in the Management of Acute Venous Thromboembolism and New Therapeutic Agents

Key Takeaway: Recent advances in venous thromboembolism management are changing practice, and novel therapeutic targets with minimal hemostasis influence may help address unmet needs.