L. Kinsell, G. Schlierf
Oct 1, 1965
Annals of the New York Academy of Sciences
Until recently there has been general acceptance of the concept tha t any patient with milky or creamy fasting plasma has an inability to metabolize properly dietary fat, i.e. t o “clear” chylomicrons from the plasma. With advances in understanding of lipid metabolism, i t has become apparent tha t this concept is not necessarily correct.’ I n fact, in the majority of subjects with fasting lipemia a significant amount of the circulating glycerides, in some instances probably all of the circulating glycerides, originate not in the alimentary tract (at least not, directly) bu t rather are derived from an endogenous source, presumably the liver.’ In this communication we shall concern ourselves initially with “pure” alimentary hyperglyceridemia which can also be called hyperchylomicronemia or fat induced hyperlipemia. We then shall give some brief consideration to nonalimentary hyperglyceridemia as well. Under this heading we include any form of hyperglyceridemia in which factors other than gross intolerance to all dietary fats play a major role.