Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress.

doi:10.1016/j.biochi.2011.12.015

Paper

Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress.

Published Apr 1, 2012 · J. Garrido, Alexandra Gaspar, E. Garrido

Biochimie

Q1 SJR score

115

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2

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Abstract

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In Vitro Study

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Study Snapshot

Alkyl esters of hydroxycinnamic acids improve their antioxidant properties and lipophilicity, enhancing their cell protective activity against oxidative stress.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress.

References

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Antioxidants show potential in preventing and treating various diseases, but more disease-specific, target-directed, highly bioavailable antioxidants are needed for success.

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CAPE, an active component in propolis, may slow or prevent the progression of Parkinson's disease and other neurodegenerative disorders by preventing dopaminergic neurodegeneration.

Neuroprotective and anti-oxidant effects of caffeic acid isolated from Erigeron annuus leaf

Caffeic acid, an active compound in Erigeron annuus leaf extracts, has antioxidative and neuroprotective effects on neuronal cells, potentially benefiting Alzheimer's disease prevention.

Effects of a multi-herbal extract on type 2 diabetes

The aqueous extract of seven hypoglycemic herbs shows potential therapeutic effects for treating type 2 diabetes in both cell and animal models.

Citations