Paper
Anti-apoptotic and anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's rat model.
Published Apr 1, 2013 · Pallavi Shrivastava, K. Vaibhav, Rizwana Tabassum
The Journal of nutritional biochemistry
Q1 SJR score
127
Citations
3
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Non-RCT
Animal Study
Highly CitedStudy Snapshot
Piperine, a compound found in Piper nigrum, exhibits anti-apoptotic and anti-inflammatory properties, improving motor coordination and balance in 6-OHDA-induced Parkinson's rats.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
Full text analysis coming soon...
References
Inhibition of lipopolysaccharide-induced inflammatory responses by piperine.
Piperine inhibits LPS-induced endotoxin shock by inhibiting type 1 interferon production.
2010·93citations·Gi-Sang Bae et al.·European journal of pharmacology
European journal of pharmacology
Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer's disease.
Piperine, the main alkaloid in Thai black pepper, significantly improves memory impairment and neurodegeneration in an animal model of Alzheimer's disease.
2010·252citations·Pennapa Chonpathompikunlert et al.·Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Mitochondrial dysfunction and biogenesis in the pathogenesis of Parkinson's disease.
Mitochondrial dysfunction and biogenesis may play a role in the pathogenesis of Parkinson's disease, offering potential treatment strategies to slow disease progression.
2009·63citations·Tsu-Kung Lin et al.·Chang Gung medical journal
Chang Gung medical journal
[Antidepressant effects of piperine and its neuroprotective mechanism in rats].
Piperine can relieve depression in chronic unpredictable mild stress rats by modulating the function of the hypothalamic-pituitary-adrenal (HPA) axis.
2009·10citations·Yuan Hu et al.·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
Citations
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2025·0citations·Abhishek A. Revankar et al.·Frontiers in Pharmacology
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2024·1citation·Fangxin Guo et al.·Molecules
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Long-term administration of MarL1 reduces Alzheimer's disease-related neuropathogenesis by curbing neuroinflammation and neurodegeneration in a transgenic mouse model.
2024·0citations·Pallavi Shrivastava et al.·Biomedicines
Biomedicines
A comprehensive review of natural compounds and their structure-activity relationship in Parkinson's disease: exploring potential mechanisms.
Natural compounds show potential neuroprotective effects and target various pathways in Parkinson's disease, potentially leading to innovative therapeutic strategies and interventions.
2024·2citations·Rana M. Merghany et al.·Naunyn-Schmiedeberg's archives of pharmacology
Naunyn-Schmiedeberg's archives of pharmacology
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson's disease.
Small molecules targeting mitochondria show promise in restoring function and mitigating neurodegeneration in Parkinson's disease, offering patients hope for better outcomes and improved quality of life.
2024·3citations·Chinmay Pal·Mitochondrion
Mitochondrion
Multiple effects of spicy flavors on neurological diseases through the intervention of TRPV1: a critical review.
Spicy flavors can enhance physiological balance and alleviate neurological diseases, with TRPV1 playing a significant role in regulating metabolism and nervous system homeostasis.
2024·0citations·Boyong Hu et al.·Critical reviews in food science and nutrition
Critical reviews in food science and nutrition
Aspects of DNA interaction with the natural heterocyclic compounds
Heterocyclic natural compounds show therapeutic potential and diverse binding modes with DNA, offering potential for new cancer treatments.
2024·0citations·M. Kamalabadi et al.·International Journal of Biology and Chemistry
International Journal of Biology and Chemistry