I. Wiser, B. Mehrara, M. Coriddi
Sep 1, 2020
Plastic and Reconstructive Surgery Global Open
RESULTS: A total of 118 patients were evaluated. Limb circumference difference underestimated lymphedema diagnosis compared to limb volume excess. Bioimpedance (L-Dex) scores highly correlated with limb volume excess (r = 0.714; P < 0.001). L-Dex scores were highly sensitive and had a high positive predictive value for diagnosing lymphedema in patients with a volume excess of 10% or more. Indocyanine green was highly sensitive in identifying lymphedema. Lymphoscintigraphy had an overall low sensitivity and specificity for the diagnosis of lymphedema. MRA was highly sensitive in diagnosing lymphedema and adipose hypertrophy as well as useful in identifying axillary vein obstruction and occult metastasis. Patients with minimal limb volume difference still demonstrated significantly impaired quality of life.