Molecular basis of metastasis.
Published Dec 25, 2008 · A. Chiang, J. Massagué
The New England journal of medicine
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Abstract
Metastases are the principal cause of death in patients with cancer. Recent advances bring hope that it will be possible to identify the molecules and processes involved in metastasis, and this new knowledge could lead to effective methods of preventing and treating metastases. This review describes the properties of cells that enable them to surmount physical boundaries, disseminate, and colonize a distant organ.
Study Snapshot
Key takeawayUnderstanding the molecular basis of metastasis could lead to effective prevention and treatment methods for cancer patients.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.