Blockade of the ATP-sensitive K+ channel by 5-hydroxydecanoate in guinea pig ventricular myocytes.

doi:10.1016/s0022-3565(25)11353-0

Paper

Blockade of the ATP-sensitive K+ channel by 5-hydroxydecanoate in guinea pig ventricular myocytes.

Published Feb 1, 1992 · T. Notsu, I. Tanaka, M. Takano

The Journal of pharmacology and experimental therapeutics

Q2 SJR score

91

Citations

1

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Highly Cited

Study Snapshot

5-hydroxydecanoate (5-HD) effectively reverses iodoacetate-induced shortened action potential duration in guinea pig ventricular myocytes by depressing the ATP-sensitive K+ channel.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

Blockade of the ATP-sensitive K+ channel by 5-hydroxydecanoate in guinea pig ventricular myocytes.

References

Citations

Dexmedetomidine Provides Cardioprotection During Early or Late Reperfusion Mediated by Different Mitochondrial K+-Channels

Dexmedetomidine provides cardioprotection during reperfusion, with its protective effect mediated by different mitochondrial K+-channels depending on the time of reperfusion.

Fatty Acid and Related Potassium Kv2 Channel Blockers: Toxicity and Physiological Actions on Mosquitoes

Decanoic acid shows greater insecticidal activity than 5-HDC, paralyzing larvae and killing mosquitoes, while TRAM-34 and rolipram show no potent effect on adult mosquitoes.

Microdialysis technique for in-vivo monitoring of •OH generation on myocardial injury in the rat

In-vivo microdialysis technique for monitoring reactive oxygen species generation on myocardial injury in rats.

Mitochondrial channels: ion fluxes and more.

Mitochondrial ion channels play crucial roles in energy supply and cell fate, with potential therapeutic perspectives based on current knowledge.

Multiplicity of effectors of the cardioprotective agent, diazoxide.

Diazoxide's cardioprotective properties may be due to its multiple effectors, which may balance multiple physiological processes during cardiac ischemia.