Calcium and vitamin D in the prevention and treatment of osteoporosis – a clinical update

doi:10.1111/j.1365-2796.2006.01655.x

Paper

Calcium and vitamin D in the prevention and treatment of osteoporosis – a clinical update

Published Jun 1, 2006 · Paul Lips, S. Boonen, D. Vanderschueren

Journal of Internal Medicine

139

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3

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Abstract

Combined calcium and vitamin D supplementation is an essential component of the management of osteoporosis, supported by a strong scientific rationale. The types of individuals who should receive calcium and vitamin D supplements are those: (i) patients with documented osteoporosis receiving antiresorptive or anabolic treatment; (ii) patients receiving glucocorticoids; and (iii) individuals with or at high risk of calcium and/or vitamin D insufficiencies, in particular older women and men. This article describes the evidence base that supports targeting these groups. Benefits are most apparent when 800 IU day−1 vitamin D is complemented with a dose of 1000–1200 mg day−1 elemental calcium. Compliance is also key to optimizing clinical efficacy.

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Study Snapshot

Combined calcium and vitamin D supplementation is essential for osteoporosis management, particularly for patients with osteoporosis, those receiving glucocorticoids, and individuals at high risk of calcium and vitamin D insufficiencies.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Calcium and vitamin D in the prevention and treatment of osteoporosis – a clinical update

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