R. Osborn, T. H. Simpson
Journal of Chromatography A
Abstract A method of characterising iodoamino acids, e.g. thyroxine, iodothyronines and iodotyrosines and some of their commonly occurring derivatives, e.g. thyrolactic, -pyruvic and -acetic acids is described. This procedure, which is based on thin layer chromatography of the parent acids and on the preparation and chromatography of suitable derivatives, prepared in sequence, is exemplified by the characterisation of 3,3′-5′-triiodothyronine, a trace metabolite of thyroxine occurring in the plasma of plaice.