The chronotherapy of hypertension: or the benefit of taking blood pressure tablets at bedtime.
Published Apr 1, 2017 · G. Vernon
The British journal of general practice : the journal of the Royal College of General Practitioners
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Abstract
The chronotherapy of hypertension is a relatively new practice in the UK. Yet the latest RCT (MAPEC)1 shows that taking blood pressure (BP) tablets at bedtime instead of in the morning (for those of our patients who are on more than one BP tablet per day) lowers the night-time blood pressure and reduces the relative risk of major cardiovascular disease (CVD) events by about 60% ( P = 0.33) over 5 years.2 This translates (very roughly) into a number needed to treat (NNT) of 300 to …
Study Snapshot
Key takeawayTaking blood pressure tablets at bedtime lowers night-time blood pressure and reduces the risk of major cardiovascular disease events by about 60% over 5 years.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.