Paper
The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy
Published Nov 14, 2013 · Y. Liu, Wei Cao, Bo Zhang
Scientific Reports
Q1 SJR score
89
Citations
5
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Magnolol, a natural compound found in medicinal herbs, inhibits breast cancer cell invasion by downregulating MMP-9 and NF-B pathways, exhibiting potential in human breast cancer therapy.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
Full text analysis coming soon...
References
Genetic susceptibility to triple-negative breast cancer.
Triple-negative breast cancer (TNBC) is associated with a unique pattern of common and rare germline predisposition alleles, highlighting the need for further genetic and epidemiologic research to better understand its etiology and develop risk prediction models.
2013·195citations·Kristen Stevens et al.·Cancer research
Cancer research
Gefitinib Analogue V1801 Induces Apoptosis of T790M EGFR-Harboring Lung Cancer Cells by Up-Regulation of the BH-3 Only Protein Noxa
V1801, a weak gefitinib analogue, overcomes drug-resistance in non-small cell lung cancer cells by activating BH-3-only pro-apoptotic proteins, offering potential therapeutic potential for this cancer type.
2012·10citations·Bo Zhang et al.·PLoS ONE
PLoS ONE
Identification of an Annonaceous Acetogenin Mimetic, AA005, as an AMPK Activator and Autophagy Inducer in Colon Cancer Cells
AA005 is a potent antitumor agent that inhibits colon cancer cell growth and induces autophagy by activating AMPK and inhibiting mTORC1.
2012·40citations·Yong-Qiang Liu et al.·PLoS ONE
PLoS ONE
Gambogenic acid induces G1 arrest via GSK3β-dependent cyclin D1 degradation and triggers autophagy in lung cancer cells.
Gambogenic acid (GEA) inhibits lung cancer cell growth and induces autophagy, potentially offering chemopreventive and therapeutic potential for lung cancer.
2012·79citations·Xian-jun Yu et al.·Cancer letters
Cancer letters
N‐(4‐hydroxyphenyl)retinamide inhibits breast cancer cell invasion through suppressing NF‐KB activation and inhibiting matrix metalloproteinase‐9 expression
N-(4-hydroxyphenyl)retinamide inhibits breast cancer cell invasion by suppressing MMP-9 expression and NF-B signaling pathway.
2012·31citations·Hyereen Kang et al.·Journal of Cellular Biochemistry
Journal of Cellular Biochemistry
Citations
Dietary Polyphenols Effects on Focal Adhesion Plaques and Metalloproteinases in Cancer Invasiveness
Dietary polyphenols from plant-based foods and beverages may have antitumoral effects by targeting key mechanisms involved in cancer progression and reducing cancer cells' invasiveness.
2024·3citations·Raffaele Carrano et al.·Biomedicines
Biomedicines
Natural compounds modulating mitophagy: Implications for cancer therapy.
Natural compounds can potentially enhance cancer therapy by modulating mitophagy, offering potential new treatment strategies.
2023·14citations·Min Cao et al.·Cancer letters
Cancer letters
Potential of alisols as cancer therapeutic agents: Investigating molecular mechanisms, pharmacokinetics and metabolism.
Alisols show promising anti-cancer properties, suppressing cancer cell proliferation and migration, with minimal side effects and low drug resistance.
2023·1citation·Yinqi Wu et al.·Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Self-assembled supramolecular nanoparticle by host-guest interaction for thermo-controlled released of magnolol in cancer chemotherapy
FA-PPG--CD supramolecular nanoparticles with magnolol effectively control drug release, enhancing cancer chemotherapy efficacy and low toxicity to normal cells.
2023·5citations·F. B. Ilhami et al.·Journal of Drug Delivery Science and Technology
Journal of Drug Delivery Science and Technology
Magnolol and Temozolomide exhibit a synergistic anti-glioma activity through MGMT inhibition.
Magnolol and Temozolomide show synergistic anti-glioma activity by inhibiting MGMT enzyme activation through NF-B pathway inhibition.
2023·5citations·Moumita Kundu et al.·Biochimica et biophysica acta. Molecular basis of disease
Biochimica et biophysica acta. Molecular basis of disease
10-Hydroxy Decanoic Acid-Based Vesicles as a Novel Topical Delivery System: Would It Be a Better Platform Than Conventional Oleic Acid Ufasomes for Skin Cancer Treatment?
HDA-based vesicles show potential as a better topical delivery system for skin cancer treatment, with enhanced permeation and drug retention compared to conventional oleic acid ufasomes.
2023·6citations·Bassant Atef et al.·Pharmaceutics
Pharmaceutics
Evaluating the Magnolol Anticancer Potential in MKN-45 Gastric Cancer Cells
Magnolol has a remarkable anti-tumor effect on MKN-45 gastric cancer cells, and when combined with cisplatin, may help overcome cisplatin resistance in gastric cancer cells.
2023·1citation·Mahsa Naghashpour et al.·Medicina
Medicina