Paper
Construction and Characterization of 3,7-Dichloro-N-(2,6-Diethylphenyl)-N-(2-Propoxyethyl)Quinolone-8-Carboxamide: A Potential Novel Pesticide Compound
Published Jan 1, 2021 · Xi-le Deng, Chun-Hui Zhu, Xiaomao Zhou
Chemistry of Heterocyclic Compounds
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Abstract
A novel compound, 3,7-dichloro- N -(2,6-diethylphenyl)- N -(2-propoxyethyl)quinoline-8-carboxamide was synthesized by splicing together a chloro-substituted quinoline moiety found in quinclorac (a selective herbicide) and a substituted amide moiety found in pretilachlor (another selective herbicide) using the active substructure splicing method. The chemical structure of this compound was characterized by 1 H, 13 C NMR, FTIR, high-resolution mass spectra and X-ray diffraction analysis. Pesticide potency (herbicidal and fungicidal activity) of this compound was evaluated. This compound displayed excellent control efficiency against Echinochloa crusgalli and also showed good fungicidal in vitro activity against Phytophthora capsici , Phytophthora sojae , and Phytophthora infestans .
The novel compound 3,7-dichloro-N-(2,6-diethylphenyl)-N-(2-propoxyethyl)quinoline-8-carboxamide shows excellent control efficiency against Echinochloa crusgalli and good fungicidal activity against
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