Iterative and regioselective cross-couplings of 2-chloro-3,4-diiodopyridine leading to 2,3,4-triheteroarylpyridines

doi:10.1016/J.TET.2009.11.066

Paper

DOI: 10.1016/J.TET.2009.11.066

Iterative and regioselective cross-couplings of 2-chloro-3,4-diiodopyridine leading to 2,3,4-triheteroarylpyridines

Published Jan 16, 2010 · Laura M. Daykin, Jamie S. Siddle, Adrian L. Ankers

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Abstract

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Study Snapshot

This study demonstrates a one-pot synthesis of 2,3,4-triheteroarylpyridines using a Directed ortho Metallation/Halogen Dance mechanism, leading to novel 2,3,4-triheteroarylpyridine scaffolds in viable yields.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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