Death attributed to severe anaphylactic reaction due to omeprazole

doi:10.3760/CMA.J.ISSN.1008-5734.2017.02.020

Paper

Death attributed to severe anaphylactic reaction due to omeprazole

Published Apr 28, 2017 · Lien He, Zhi-guang Qiu, Yinling Ma

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Abstract

A 61-year-old female patient with stomach discomfort received omeprazole enteric coated tablet 40 mg once daily. On day 3 of administration of omeprazole, she presented sporadic erythema and stopped the medicine by herself. Three days after drug withdrawal, her symptom of erythema improved. She received omeprazole enteric coated tablet at the previous dosage again. Two days after taking medicine again, the patient developed rash all over her body, severe diarrhea and vomiting, acute renal injury and allergic shock in succession. She was diagnosed as severe allergic reaction due to omeprazole. The patient received the treatments of antianaphylaxis, maintaining the function of circulatory system, fluid infusion, and continuous veno venous hemodiafiltration. But the therapeutic effect was poor. The patient died on the second day after giving up the treatment which decided by her family members. Key words: Omeprazole; Anaphylaxis; Death

Case Report

Study Snapshot

Omeprazole can cause severe anaphylactic reactions, leading to death in a 61-year-old female patient.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Death attributed to severe anaphylactic reaction due to omeprazole

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