Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial
Published 2005 · M. Maurer, V. Henn, A. Dittrich
European Archives of Psychiatry and Clinical Neuroscience
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Abstract
SummaryA double-blind study was performed comparing 5 mg delta-9-tetrahydrocannabinol (THC) p.o., 50 mg codeine p.o., and placebo in a patient with spasticity and pain due to spinal cord injury. The three conditions were applied 18 times each in a randomized and balanced order. Delta-9-THC and codeine both had an analgesic effect in comparison with placebo. Only delta-9-THC showed a significant beneficial effect on spasticity. In the dosage of THC used no altered consciousness occurred.
Study Snapshot
Key takeawayDelta-9-tetrahydrocannabinol (THC) effectively reduces spasticity and pain in spinal cord injury patients, while both codeine and THC show analgesic effects without altering consciousness.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.