Paper
Design, synthesis, and biological activity of novel 4-(3,4-dimethoxyphenyl)-2-methylthiazole-5-carboxylic acid derivatives.
Published Jun 1, 2004 · Changling Liu, Lin Li, Zhengming Li
Bioorganic & medicinal chemistry
Q2 SJR score
19
Citations
0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Novel 4-(3,4-dimethoxyphenyl)-2-methylthiazole-5-carboxylic acid derivatives show promising fungicidal and insecticidal activities at 375 g ai/ha and 600 g ai/ha, respectively.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
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Synthesis of Amide Derivatives of Pyrimidine-Triazolo[1,5-a]pyridin-7-yl) Thiazoles: In Vitro Anticancer Evaluation and In Silico Molecular Binding Studies
Compound 21a, a pyrimidine-triazolo[1,5-a]pyridin-7-yl)thiazole derivative, shows remarkable anticancer activity against MCF-7 and A549 cell lines, with improved interaction energy and profile.
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Design, Synthesis, Anticancer Evaluation, and Molecular Docking Studies of Thiazole–Pyrimidine Linked Amide Derivatives
The amide-based thiazole-pyrimidines (13a-j) show potential as multi-acting anticancer agents, with 13b and 13h showing maximum anti-cancer activity against various human cancer cell lines and superior to reference standard Etoposide.
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Design, Synthesis, and Anticancer Evaluation of N-(4-{5-[4-(5-Methyl-1,3,4-oxadiazol-2-yl)phenyl]-4-(2,3,4-trimethoxyphenyl)-1,3-thiazol-2-yl}phenyl)benzamides
The synthesized compounds showed moderate to excellent anticancer activity against various cancer cell lines, with five derivatives outperforming the reference drug etoposide.
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Crystal structure and Hirshfeld surface analysis of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-N-(pyridin-2-ylmethyl)benzamide
The crystal structure of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-N-(pyridin-2-ylmethyl)benzamide reveals two independent molecules with different orientations of the pyridine ring compared to the benzene ring.
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Design, Synthesis, and Anticancer Evaluation of 2-{3-{4-[(5-Aryl-1,2,4-oxadiazol-3-yl)methoxy]phenyl}isoxazol-5-yl}-N-(3,4,5-trimethylphenyl)thiazol-4-amine Derivatives
New 2-3-4-[(5-aryl-1,2,4-oxadiazol-3-yl)methoxy]phenyl-isoxazol-5-yl-N-(3,4,5-trimethylphenyl)thiazol-4-amine derivatives show good to
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