Detection of cytokines in skeletal muscle tissue using optical SPR sensing platform
Víctor Parra-Monreal, María A. Ortega-Machuca, J. Ramón‐Azcón
Jun 9, 2021
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2021 13th Spanish Conference on Electron Devices (CDE)
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Key Takeaway Key Takeaway: SPR technology can effectively detect IL-6 in muscle tissue, potentially aiding in the diagnosis of muscular dystrophies.
Abstract
In this work we have explored the use of a Surface Plasmon resonance (SPR) phenomenon for the detection of interleukin-6 (IL-6), a pro-inflammatory cytokine. It plays an important role in the muscle tissues, having direct relation with muscle contraction and, thus, it is considered a biomarker for some types of muscular dystrophies. Here we show that SPR can be used as a real-time monitoring of the shift of the reflectance dip of a gold diffraction grating in front to the antibody adhesion to gold.
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