The reaction of 3-methyl-1-[6-methyl-2-(methylsulfanyl)pyrimidin-4-yl]-4-[(phenylimino)methyl]-1H-pyrazol- 5-ol with heterocyclic CH acids is accompanied by a formal cleavage of the substrate and the formation of substituted 1-(pyrimidin-4-yl)pyrazole and aniline. The possibility of isolation of the azomethine (aminomethylеne) derivative of CH acids formed in the process depends on the electrophilicity of its α-carbon atom. In the case of increased electrophilicity, this compound reacts in situ with CH acid to form methylеne bis-СН acids with elimination of aniline.

The domino reaction of 3-methyl-1-[6-methyl-2-(methylsulfanyl)pyrimidin-4-yl]-4-[(phenyl-Imino)methyl]-1H-pyrazol-5-ol with heterocyclic ch acids leads to the formation of substituted 1-

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A Domino Reaction of 3-Methyl-1-[6-Methyl-2-(Methylsulfanyl)Pyrimidin-4-yl]-4-[(Phenyl-Imino)Methyl]-1H-Pyrazol-5-ol with Hetero-Cyclic ch Acids

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