Dynorphin and the pathophysiology of drug addiction.
Published Nov 1, 2007 · T. Shippenberg, A. Zapata, V. Chefer
Pharmacology & therapeutics
363
Citations
24
Influential Citations
Abstract
Abstract removed due to Elsevier request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Key takeawayRepeated drug use up-regulates the dynorphin/kappa-opioid receptor system, contributing to dysregulation of behavior and individual vulnerability to cocaine and alcohol effects.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.