Paper
The effect of NeuroAiD™ (MLC601) on cerebral blood flow velocity in subjects' post brain infarct in the middle cerebral artery territory.
Published Oct 1, 2011 · Reza Bavarsad Shahripour, G. Shamsaei, H. Pakdaman
European journal of internal medicine
Q1 SJR score
42
Citations
4
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
RCTStudy Snapshot
MLC601 treatment may increase cerebral blood flow in stroke patients, potentially improving functional recovery measures.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
Full text analysis coming soon...
References
Neuroprotective and neuroproliferative activities of NeuroAid (MLC601, MLC901), a Chinese medicine, in vitro and in vivo
NeuroAid (MLC601) and MLC901 treatments improve survival, protect the brain from ischemic injury, and decrease functional deficits in stroke patients.
2010·115citations·C. Heurteaux et al.·Neuropharmacology
Neuropharmacology
Safety Profile of MLC601 (Neuroaid®) in Acute Ischemic Stroke Patients: A Singaporean Substudy of the Chinese Medicine Neuroaid Efficacy on Stroke Recovery Study
MLC601 (Neuroaid®) is safe for acute stroke patients receiving a 3-month treatment, with no significant differences in laboratory safety data compared to placebo.
2010·49citations·S. Young et al.·Cerebrovascular Diseases
Cerebrovascular Diseases
Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132
FMRP-associated microRNAs miR-125b and miR-132 influence synaptic structure and function in hippocampal neurons, potentially impacting fragile X syndrome pathophysiology.
2010·1072citations·Dieter Edbauer et al.·Neuron
Neuron
Excessive Incidence of Stroke in Iran: Evidence From the Mashhad Stroke Incidence Study (MSIS), a Population-Based Study of Stroke in the Middle East
The incidence of stroke in Iran is significantly greater than in most Western countries, with stroke occurring at younger ages and ischemic stroke incidence being significantly higher than reported in other regions.
2010·230citations·M. Azarpazhooh et al.·Stroke
Stroke
A Double-Blind, Placebo-Controlled, Randomized Phase II Pilot Study to Investigate the Potential Efficacy of the Traditional Chinese Medicine Neuroaid (MLC 601) in Enhancing Recovery after Stroke (TIERS)
Neuroaid showed a positive trend for improvement in motor recovery in ischemic stroke patients, but a larger multicenter trial focusing on severe stroke patients is needed for further evaluation.
2009·48citations·K. Kong et al.·Cerebrovascular Diseases
Cerebrovascular Diseases
Citations
Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOke Subjects with mOtor deficits (MAESTOSO) study protocol.
MLC1501 shows potential in enhancing long-term recovery and safety after brain injury in patients with ischaemic stroke.
2025·0citations·C. Chen et al.·Stroke and vascular neurology
Stroke and vascular neurology
Translational Medicine in Acute Ischemic Stroke and Traumatic Brain Injury—NeuroAiD Trials, from Traditional Beliefs to Evidence-Based Therapy
MLC901 significantly reduces recovery time for acute ischemic stroke and traumatic brain injury by 18 months compared to a placebo, potentially improving health outcomes and reducing healthcare costs.
2024·0citations·N. Venketasubramanian et al.·Biomolecules
Biomolecules
The role of traditional herbal medicine for ischemic stroke: from bench to clinic-A critical review.
Traditional herbal medicine (THM) combined with Western medicine can significantly improve neurological function and accelerate recovery time in ischemic stroke patients, with fewer adverse effects.
2022·9citations·Dan-Li Hao et al.·Phytomedicine : international journal of phytotherapy and phytopharmacology
Phytomedicine : international journal of phytotherapy and phytopharmacology
Randomised, double-blind, placebo-controlled study investigating Safety and efficAcy of MLC901 in post-traUmatic bRAin Injury: the SAMURAI study protocol
MLC901 shows potential in improving cognitive function and quality of life after mild traumatic brain injury.
2022·2citations·P. Pilipenko et al.·BMJ Open
BMJ Open
Systematic Review and Meta-Analysis of the Efficacy of MLC901 (NeuroAiD IITM) for Acute Ischemic Brain Injury in Animal Models
MLC901 administration in animal stroke models effectively reduced infarction volume and improved neurologic function, potentially aiding in its efficacy for acute ischemic brain injury in humans.
2021·5citations·I. A. R. Ranuh et al.·Journal of Evidence-based Integrative Medicine
Journal of Evidence-based Integrative Medicine
Clinical Outcomes of MLC601 (NeuroAiDTM) in Traumatic Brain Injury: A Pilot Study
MLC601 showed potential for a positive effect on clinical outcomes in nonsurgical moderate TBI patients without adverse effects.
2020·8citations·Asra Al Fauzi et al.·Brain Sciences
Brain Sciences
Safety and efficacy of recovery-promoting drugs for motor function after stroke: A systematic review of randomized controlled trials.
Selective serotonin reuptake inhibitors and levodopa show potential in promoting motor recovery after stroke, but the high risk of bias in many trials is concerning.
2019·7citations·Nerida Firth et al.·Journal of rehabilitation medicine
Journal of rehabilitation medicine
The Traditional Chinese Medicine MLC901 inhibits inflammation processes after focal cerebral ischemia
MLC901 treatment reduces brain damage and mortality rates after cerebral ischemia, potentially contributing to its potential therapeutic value.
2018·33citations·C. Widmann et al.·Scientific Reports
Scientific Reports
An evaluation of the role of mixing techniques in the observed variation in acetylcysteine infusion concentrations
Mixing techniques do not significantly impact acetylcysteine infusion concentrations, suggesting that small errors in infusion preparation are the cause of variations in drug concentrations.
2018·4citations·K. Layne et al.·British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology