Paper

Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo‐Controlled, Crossover Comparison Studies

Published Jan 1, 2011 · D. Angiolillo, C. M. Gibson, S. Cheng

Clinical Pharmacology & Therapeutics

286

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Abstract

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Study Snapshot

A metabolic drug-drug interaction exists between clopidogrel and omeprazole, but not between clopidogrel and pantoprazole, with no significant differences observed between the two drugs.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo‐Controlled, Crossover Comparison Studies

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