Paper
A novel cellular engineering approach to diabetes mellitus
Published Jul 14, 2020 · G. Weir
Nature Reviews Endocrinology
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Abstract
For type 1 diabetes mellitus (T1DM), keeping glucose levels within the normal range of 65–150 mg/dl with administered insulin has had limited success. Now, Fussenegger and colleagues have engineered cells to release insulin in response to electrical signals, but can this advance lead to better glucose control?
Study Snapshot
Key takeawayCells engineered to release insulin in response to electrical signals show potential for better glucose control in type 1 diabetes mellitus patients.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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