A series of potential biologically active substituted 2,5-di(4 aryloylaryloxymethyl)-1,3,4-oxadiazoles 9a-j were evaluated for its potential antimicrobial activity comparing with the standard drugs-Streptomycin and Ketoconazole respectively. Compound 9a with fluoro group exhibited highest activity against both gram-positive and gramnegative bacteria. Compounds 9a with fluoro group and 9c with fluoro and bromo showed good activity against antifungal activities.

Substituted 2,5-di(4 aryloylaryloxymethyl)-1,3,4-oxadiazoles 9a-j show potential antimicrobial activity, with compound 9a showing the highest activity against both gram-positive and gramnegative bacteria, and compounds 9a and 9

Paper

Biological Evaluation of 2, 5-Di (4 Aryloylaryloxy Methyl) - 1, 3,4-Oxadiazoles Derivatives as Antimicrobial Agents

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