Paper

Extended release of a large amount of highly water-soluble diltiazem hydrochloride by utilizing counter polymer in polyethylene oxides (PEO)/polyethylene glycol (PEG) matrix tablets.

Published Oct 1, 2008 · K. Yoshihara, H. Kondo, H. Kojima

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

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Abstract

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In Vitro Study

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Study Snapshot

Using a counter polymer in PEO/PEG matrix tablets can effectively extend the sustained release of highly water-soluble drugs like diltiazem hydrochloride for 24 hours or longer.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Extended release of a large amount of highly water-soluble diltiazem hydrochloride by utilizing counter polymer in polyethylene oxides (PEO)/polyethylene glycol (PEG) matrix tablets.

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