Flipping the Metabolic Switch: Understanding and Applying Health Benefits of Fasting
Published Oct 31, 2017 · S. Anton, Keelin Moehl, W. Donahoo
Obesity (Silver Spring, Md.)
445
Citations
27
Influential Citations
Abstract
Intermittent fasting (IF) is a term used to describe a variety of eating patterns in which no or few calories are consumed for time periods that can range from 12 hours to several days, on a recurring basis. This review is focused on the physiological responses of major organ systems, including the musculoskeletal system, to the onset of the metabolic switch: the point of negative energy balance at which liver glycogen stores are depleted and fatty acids are mobilized (typically beyond 12 hours after cessation of food intake).
Study Snapshot
Key takeawayIntermittent fasting, when no or few calories are consumed for periods of 12 hours to several days, can lead to physiological responses in major organ systems, including the musculoskeletal system, that can improve health.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.