Paper

Gabapentin regulates expression of FGF2 and FGFR1 in dorsal root ganglia via microRNA-15a in the arthritis rat model.

Published Nov 1, 2017 · Dexu Sun, Jun-xian Yang, Deguang Wang

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association

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Abstract

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RCT

Animal Study

Study Snapshot

Gabapentin may relieve arthritis pain and reduce the expression of FGF2 and FGFR1 in dorsal root ganglia, with microRNA-15a playing a regulatory role in this process.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Gabapentin regulates expression of FGF2 and FGFR1 in dorsal root ganglia via microRNA-15a in the arthritis rat model.

References

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