Paper
Gabapentinoids for treatment of alcohol use disorder: A systematic review and meta‐analysis
Published Jul 15, 2020 · Wei-Lieh Huang, Ying-Chih Cheng, Yu-Chen Huang
Human Psychopharmacology: Clinical and Experimental
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Influential Citations
Abstract
Gabapentin (GBP) and pregabalin (PGB) have been used to treat alcohol use disorder (AUD) and alcohol withdrawal, but with inconsistent results. In this meta‐analysis, we explored the effects of GBP/PGB treatment on AUD and their effects on withdrawal, craving, depression, and sleep disturbance in AUD patients.
Meta-AnalysisStudy Snapshot
Gabapentin and pregabalin show mixed results in treating alcohol use disorder and alcohol withdrawal, with mixed results in reducing cravings, depression, and sleep disturbances.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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