Galactofuranosylated Galactocerebrosides, a New Drug Delivery System for Ceramides to Colon
D. Iga, Silvia Iga
Jun 9, 2008
Citations
2
Citations
Journal
The Open Organic Chemistry Journal
Full text
Semantic Scholar
Key Takeaway Key Takeaway: Galactofuranosylated galactocerebrosides show potential as a new drug delivery system for ceramides to the colon, with potential for use in pharmacological treatments.
Abstract
Two isomeric partially acetylated galactocerebrosides, s-D-galactopyranosyl (2,3,4-tri-O-acetyl)- and s-D- galactopyranosyl (2,4,6-tri-O-acetyl)-1'(3'-O-acetyl)ceramide, were prepared from galactocerebroside and sulfatide, re- spectively. Their galactofuranosylation produced s-D-galactofuranosyl-6- and s-D-galactofuranosyl-3-s-D- galactopyranosyl-1'ceramide, as demonstrated by 1 H and 13 C NMR spectra as well as by chemical means. 1 H and 13 C NMR spectroscopy.
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