The impact of probiotics and prebiotics on the immune system
Published Sep 25, 2012 · T. Klaenhammer, M. Kleerebezem, M. Kopp
Nature Reviews Immunology
272
Citations
3
Influential Citations
Abstract
Probiotics and prebiotics are increasingly being added to foodstuffs with claims of health benefits. Probiotics are live microorganisms that are thought to have beneficial effects on the host, whereas prebiotics are ingredients that stimulate the growth and/or function of beneficial intestinal microorganisms. But can these products directly modulate immune function and influence inflammatory diseases? Here, Nature Reviews Immunology asks four experts to discuss these issues and provide their thoughts on the future application of probiotics as a disease therapy.
Study Snapshot
Key takeawayProbiotics and prebiotics may modulate immune function and influence inflammatory diseases, but their future application as disease therapy remains uncertain.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.