China Modern Doctor
Objective To discuss influence and curative effect observation of Ramuli Cinnamomi Decoction Added with Puerariae on serum nitric oxide(NO) and endothelin(ET) levels of patients with vertebral artery type of cervical spondylosis. Methods A total of 82 cases of patients with vertebral artery type of cervical spondylosis were divided into observation group and control group at random. The patients in two groups were given cervical traction. The patients in observation group were additionally given Ramuli Cinnamomi Decoction Added with Puerariae though the mouth by addition and subtraction, one dose daily for 14 days. The changs of serum NO and ET levels of patients in two groups were observed and compared before and after treatment, and the clinical curative effect analysis was carried on as well.Results After 14 days medical treatment,serum NO levels of patients in two groups were obviously declined than before(P0.01 or P0.05),while ET level were obviously rose, and the declining or rising rate in observation group were much higher than that in control group(P 0.05). The total clinical efficiency of patients in observation group was92.68%, which was much higher than that in control group(75.61%)(χ2=4.48,P0.05). There weren't obviously adverse drug reactions during treatment in two groups. Conclusion Ramuli Cinnamomi Decoction Added with Puerariae has reliable curative effect and safety on vertebral artery type of cervical spondylosis, whose mechanism of action has close effect on reducing serum NO level, rising serum ET level,and protecting and adjusting vascular endothelial dysfunction.