Ischemic mitral regurgitation (IMR) is a common complication after acute myocardial infarction (AMI) [1]. IMR represents a distinct clinical disorder from degenerative mitral regulation (MR). IMR has a broad spectrum from the acute to chronic phase. Acute MR occurs when papillary muscles suddenly rupture, which is one of the devastating mechanical complications of AMI. In contrast, chronic IMR results from progressive left ventricular remodeling late after AMI, in which lateral or inferior wall infarctions are more frequent compared with anterior wall infarctions [2]. Herein, I focus on chronic IMR and summarize the mechanism, prognosis, diagnosis, and treatments based upon literature published over the last decade.

Chronic ischemic mitral regurgitation (IMR) occurs after acute myocardial infarction due to progressive left ventricular remodeling, with lateral or inferior wall infarctions more common than anterior wall infarctions.

Ischemic mitral regurgitation: Focusing on the imbalance of two intraventricular forces

Key Takeaway: Chronic ischemic mitral regurgitation (IMR) occurs after acute myocardial infarction due to progressive left ventricular remodeling, with lateral or inferior wall infarctions more common than anterior wall infarctions.