Isobutylmethylxanthine stimulates adenylate cyclase by blocking the inhibitory regulatory protein, Gi.

doi:10.1016/s0026-895x(25)08638-9

Paper

Isobutylmethylxanthine stimulates adenylate cyclase by blocking the inhibitory regulatory protein, Gi.

Published Jul 1, 1988 · W. J. Parsons, V. Ramkumar, Gary L. Stiles

Molecular pharmacology

Q1 SJR score

96

Citations

1

Influential Citations

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Highly Cited

Study Snapshot

Isobutylmethylxanthine (IBMX) increases cAMP production by blocking the inhibitory regulatory protein, Gi, which may explain some physiological effects of methylxanthines beyond phosphodiesterase inhibition or A1 adenosine receptors.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

Isobutylmethylxanthine stimulates adenylate cyclase by blocking the inhibitory regulatory protein, Gi.

References

Citations

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