Paper

Combined lithium and valproate treatment and subsequent withdrawal: Serotonergic mechanism of their interaction in discrete brain regions

Published Dec 31, 1985 · G. S. Shukla

Progress in Neuro-Psychopharmacology and Biological Psychiatry

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Study Snapshot

Combined administration of lithium and valproate leads to persistent decrease in 5-hydroxytryptamine synthesis and turnover in the brain, even after 2 days of treatment withdrawal.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Combined lithium and valproate treatment and subsequent withdrawal: Serotonergic mechanism of their interaction in discrete brain regions

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