Paper

LTD-like molecular pathways in developmental synaptic pruning

Published Sep 27, 2016 · C. Piochon, M. Kano, C. Hansel

Nature Neuroscience

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Abstract

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Literature ReviewVery Rigorous JournalHighly Cited

Study Snapshot

LTD and synaptic pruning share molecular components, suggesting they are two developmental stages of the same type of synaptic modulation that serve different but related functions in neural circuit plasticity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

LTD-like molecular pathways in developmental synaptic pruning

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