V. M. Hutchings, P. Sweny, O. Fernando
Apr 1, 1984
The British journal of radiology
Glomerular filtration rate (GFR) is an essential measurement of renal function in renal transplant patients. Although endogenous creatinine clearance is commonly used to assess GFR, the technique is inaccurate in patients with proteinuria (Favre & Wing, 1968; Hilton et al, 1969). This condition is commonly found in renal transplant patients. GFR can be reliably measured with 51Cr ethylenediamine tetra-acetic acid (EDTA) in patients with renal disease using blood samples taken over several hours (Hilton et al, 1969; Chantler et al, 1969). However repeated blood sampling is often a problem in renal transplant patients as there may be difficulty with vascular access, avoidance of shunts and fistulas being essential.