Paper

Mechanistic investigation of the negative food effect of modified release zolpidem

Published May 1, 2017 · Cord J. Andreas, X. Pepin, Constantinos Markopoulos

European Journal of Pharmaceutical Sciences

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Abstract

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In Vitro Study

Study Snapshot

Combining biorelevant dissolution testing and modeling approaches can help understand the absorption of zolpidem from various formulations, potentially reducing the negative food effect.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Mechanistic investigation of the negative food effect of modified release zolpidem

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